The most expensive Venom comic is, without rival, Amazing Spider-Man #300 (May 1988), the first full appearance of Venom under a Todd McFarlane cover: a €528.99 eBay median (101 active listings, June 2026) and a documented record sale of $13,500 in high grade. Behind it, the original black suit (#252), the first full Venom cover (#316) and the first Carnage appearance (#361) round out the top tier. Here's the ranking, grounded in real values.

Venom debuted in 1988 (Copper/Modern age), so there is no true "Silver Age" grail of the character. The highest-value issues are concentrated in a handful of Spider-Man first appearances, plus a few 1990s solo series.

This guide sticks to the verifiable: real-time eBay medians (via our estimator, limited to Amazing Spider-Man) and documented sale records. When a precise figure can't be verified, we state it qualitatively rather than inventing it.

The Venom grail ranking (real values, June 2026)

Values = median of active eBay listings, all editions and grades combined (our estimator, eBay.fr + eBay.com). The record sale is the best documented public transaction, generally in high-grade CGC.

IssueSignificanceeBay medianDocumented record
Amazing Spider-Man #300 (May 1988)First full Venom appearance, McFarlane cover€528.99 · 101 listings$13,500
Amazing Spider-Man #252 (1984)First black suit (Earth-616)€243.80 · 99 listings
Amazing Spider-Man #316 (1989)First full Venom cover€207.78 · 100 listings$5,000 (CGC 9.9)
Amazing Spider-Man #361 (1992)First Carnage appearance€115 · 101 listings$1,800

Record sources: SellMyComicBooks, GoCollect, QualityComix.

Why #300 tops the ranking

Amazing Spider-Man #300 is the undisputed grail of the symbiote family, and by far the most liquid. Three concrete reasons:

Venom grails with no direct eBay value

Some major issues aren't indexed by our estimator (limited to Amazing Spider-Man). They're no less sought after:

Collector strategy (grounded in real data)

Own a Venom comic? Get a free valuation with our tool based on real eBay sales to find its low, median and high value.